Articles Tagged With:
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Acute Small Fiber Neuropathy
Acute-onset small fiber neuropathy most often is precipitated by infections, medication side effects, or vaccinations. Most cases recover spontaneously.
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Cholinergic Basal Forebrain Involvement in Posture, Gait, and Cognitive Impairment in Parkinson’s Disease
The features of gait difficulty, postural instability, and cognitive deficits in patients with Parkinson’s disease appear to be attributable to degeneration of cholinergic basal forebrain systems, including loss of fiber tract integrity and reduction of cortical projections.
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Medications for Progressive Supranuclear Palsy: A Note of Caution
In this post hoc secondary analysis of a Phase II/III randomized clinical trial of davunetide for progressive supranuclear palsy (PSP), investigators found that patients with PSP prescribed benzodiazepine derivatives experienced more rapid worsening of their PSP Rating Scale scores over time.
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Neuropeptides in Patients with Restless Legs Syndrome
The diurnal onset of restless legs syndrome (RLS) has been replicated in a mouse model using central instillation of the main melanocortin agonist, α-MSH, which stimulates excessive locomotion and grooming in rodents as well as a state of hyperalgesia. The actions of β-endorphin (β-EDP) oppose those of α-MSH, since β-EDP promotes passivity and analgesia. In this study, these prohormones were measured in plasma and cerebrospinal fluid in patients with RLS and compared to controls. Patients with RLS had elevated levels of α-MSH and lower levels of β-EDP compared to the control group.
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Posterior Cortical Atrophy: An Important Variant of Alzheimer’s Disease
This is the first comprehensive international study of patients with posterior cortical atrophy, including clinical, biomarker, and pathology data from 1,092 patients. These patients present at a younger age, have a very high prevalence of amyloid positivity on cerebrospinal fluid studies and positron emission tomography, and 94% had autopsy evidence of Alzheimer’s disease.
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Using Genetic Testing to Improve Patient Health
To begin shifting from a reactive to a more proactive approach to healthcare, researchers and providers are taking notice of genetic testing and its benefits in making medical decisions.
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Motivational Interviewing for Better Patient Care
Motivational interviewing has been used for decades in substance abuse counseling and is now growing in use in healthcare settings to provide better care for patients and encourage health behavior change. Case managers can use motivational interviewing as a tool to provide patient-centered care that does not come across as judgmental, but rather supports and enhances a person’s motivation to change.
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Emotional Support Is Important to Caregivers of Children with Emotional-Behavioral Disorders
Parents raising children with developmental, emotional, or behavioral issues face substantial stress. Researchers studied whether adequate care coordination could improve their ability to cope with the strain, finding that it was very helpful for these families.
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Lipedema Affects More Patients than Case Managers Realize
Millions of women live with lipedema, a bilateral loose connective tissue disorder. Too few clinicians diagnose the disease — and too few women know they have it. As case managers work with patients who show signs of lipedema, there could be an opportunity to connect them to their physician for a lipedema evaluation.
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Communication Tools Can Prevent Medication Errors After Discharge
A discharge medication communication bundle can help prevent liquid medication errors when caregivers treat children at home after hospital discharge, new research shows. The communication bundle resulted in fewer caregivers making medication errors when compared with a group receiving standard care.